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Role of IgA in the defense against respiratory infections IgA deficient mice exhibited increased susceptibility to intranasal infection with Mycobacterium bovis BCG

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Within cells (principally the liver where it is stored) the folic acid found in enriched food and in vitamin supplements is converted first to dihydrofolate (DHF) and then to tetrahydrofolate (THF also H 4 folate) through the action of dihydrofolate reductase, an NADPH-requiring enzyme