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The liver changes ammonia, a toxic by product of protein metabolism into urea, which is excreted in the urine

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Rule of thumb: If you are on any long-term prescription medication, show the supplement label to your doctor or pharmacist before you begin

Because phenylephrine is a potent -1-agonist, it dramatically increases peripheral vascular resistance and afterload (Medical Advisory Board 2026a)

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While it is naturally found in the body, levels can be reduced by factors such as age, stress, and poor nutrition