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Therapeutic potential of tyrosine-protein kinase MET in osteosarcoma

Documented clinical safety signals across the peptide class include a halted clinical trial following a fatal cardiac event, case reports of melanoma and kidney dysfunction, and a documented death following intravenous administration

10.1007/s00253-016-7400-4 265 ShinD.ChoiW.BaeH

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Liver fat: At 24 weeks, mean relative LF change 43% (1 mg), 57% (4 mg), 81% (8 mg), 82% (12 mg) vs +0.3% placebo

10.1016/j.lfs.2018.05.014 145 LiB.SunC.SunJ.YangM
