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The circuit breaker in fibromyalgia is called the hypothalamus, an almond sized control center in the brain that regulates sleep, hormones, and autonomic functions like blood pressure and gut activity

PMID: 12095637 Hameed M, Orrell RW, Cobbold M, Goldspink G, Harridge SD (2003) Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise

and Dosler, S., Antimicrob
Of note, increased CGRP content has been found in the airway submucosal glands of humans with CF, as well as in mice, ferrets, and pigs with CF [161]

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These findings suggest that ferroptosis may act as a double-edged sword in the context of sepsis, as it can both exacerbate bacterial invasion and sepsis progression, while also contributing to the elimination of pathogens by immune cells
