glutathione-dependent detoxification pathway Dysregulation of Glutathione Homeostasis in Neurodegenerative Diseases Glutathione-dependent redox homeostasis is critical
Description
doi: 10.1172/JCI148550 222 GrossMIDemoSDDennisonJBChenLChernov-RoganTGoyalBet al
That is, targeting pathways that detoxify reactive metabolites may be an approach for treating tumors by potentiating, rather than repressing, a cancer metabolism phenotype
LncRNA P53RRA can bind to Ras GTPase activating protein binding protein 1 (G3BP1) to activate the p53 pathway and retain more p53 in the nucleus, thereby exerting a pro-ferroptosis effect [170]
Pay attention to dosing
Vandevijvere, S
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