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Description
Notably, overexpression of PHGDH in non-malignant breast epithelial cells induces an increase in cell proliferation associated with the alteration in cellular serine metabolism observed in tumorigenesis 8
In contrast, the non-thiol-containing ROS scavenger -Tocopherol ( -Toc) only partially rescued RH30, but not RD cells from AUR/BSO-induced ROS production and cell death, whereas it protected both RMS cell lines from AUR/ERA-induced ROS production and cell death (Figures 2a and b)
diarrhea is dose-limiting toxicity CAPOX (capecitabine + oxaliplatin): Oral alternative to FOLFOX
Think of free radicals like tiny sparks in a forest
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doi: 10.1016/j.cocis.2020.101413 98 GhezziP
