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It also increases the level of oxidative stress by decreasing the level of GSH (the reduced form of glutathione) and increases the level of MDA and activates markers of autophagy (LC3B, Beclin-1) [95]

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[DOI] [Google Scholar] 52.Lin J.Y., Selim M.A., Shea C.R., Grichnik J.M., Omar M.M., Monteiro-Riviere N.A., Pinnell S.R

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[52] GPCRs respond to extracellular signals mediated by a huge diversity of agonists, ranging from proteins to biogenic amines to protons, but all transduce this signal via a mechanism of G-protein coupling

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