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[21] Systemic symptoms, including fevers, chills, night sweats, fatigue and weight loss may be seen with bronchiectasis

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Notably, mRNA expression of Igfbp genes Igfbp2, Igfbp3 and Igfbp5 was found significantly depleted, and Igfbp4 levels significantly increased upon LLC challenge only in Igf1r fl/fl mice

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