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Dithiothreitol (60 mmol/L in 0.1 mol sodium tetraborate/L) was added to convert oxidized glutathione (GSSG) to GSH and was then alkylated by adding iodoacetamide (0.5 mol/L) in 0.1 mol ammonium bicarbonate/L

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To achieve clinical improvement in pigmentation, one can limit the activation of melanocytes, the synthesis of melanin, or the transfer of melanin

Zhang Z, Lin T, Meng Y, et al