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The possibility that NHR-49 may occupy different genomic sites in different tissues represents another challenge, and highlights that the genes regulated by NHR-49 in each tissue are not known

An action directly inside the cells: the easy penetration of liposomes into the cells allows a release of higher quantities of vitamin C directly inside the cells and amplify the beneficial effects of the vitamin [14]

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In some cases, the melanotic tumors can undergo phenotypic changes into amelanotic metastatic tumors similar to human melanomas (72)

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