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doi:10.1038/79936 pmid:11017079 Devi L, Raghavendran V, Prabhu BM, Avadhani NG, Anandatheerthavarada HK (2008) Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain

The schematic is illustrative and does not imply exhaustive coverage of all potential targets or agents.)

Among these transporting processes, the receptor-mediated transporting process responsible for transferrin was the most investigated process and some of the brain targeting agents based on the process have been used effectively to develop brain targeting drug delivery systems

[DOI] [PubMed] [Google Scholar] 50.Wakade C., Chong R., Bradley E., Thomas B., Morgan J

Aging and Parkinsons disease: different sides of the same coin

Additionally, oxidative stress in excess is understood to participate in the dysregulation of cellular processes and disease development (Zewen et al
