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If the BBB is compromised by damage or infection, water and salts can infiltrate brain tissue, causing an increase in intracranial pressure and swelling

Wu HM1, Tzeng NS, Qian L, Wei SJ, Hu X, Chen SH, Rawls SM, Flood P, Hong JS, Lu RB (2009) Novel neuroprotective mechanisms of memantine: Increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation

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204 Bao, G

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As mentioned above, Wegovy can stay at room temperature for up to 28 days