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However, when inflammation and iron overload in cells occur, the expression of hepcidin is also increased (Lieblein-Boff et al., 2013
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Histamine Histamine (2-[4-imidazolyl]ethylamine) is a bioactive amine that is synthesized by decarboxylation of its precursor amino acid, histidine, in an enzymatic reaction first described by Windaus and Vogt in 1907 involving L-histidine decarboxylase (EC 4.1.1.22) (Figure 1) [2]
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The severity of a B12 deficiency plays a key role, as does the type and severity of nerve pain
