melanotic macules. Labial Lentigo (labial macule) Differential Diagnosis of Pigmented Lesions

It rests upon eight round columns, a little more than three feet in diameter, and ten feet high from the ground to the spring of the arches

Int J Obesity 2024;48:964-72

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Case Summary Although rare, MMNSTs are crucial to identify on imaging because they are aggressive and prone to metastasizing On MRI, MMNSTs demonstrate characteristic T1 hyperintensity and T2 hypointensity related to intratumoral melanin Characteristic morphologic features and loss of PRKAR1A expression help to distinguish MMNSTs from morphologic mimics, in particular metastatic melanoma and melanoma arising from a cellular blue nevus Surgical resection of the tumor should focus on safe and complete resection and should be en bloc when possible, given the variable metastatic and malignant potential of the tumor

and despite increasing insights into the underlying pathophysiological mechanisms, the development of CIPN is currently not preventable

doi: 10.1530/JME-13-0061