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This is unsurprising as the RPE has a high level of metabolic activity, and therefore oxygen demand, making it a significant source of ROS [17]
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Moreover, no gene encoding the peptides particular sequence has ever turned up in the human genome or the gut microbiome

J Oral Biol Craniofacial Res
Plant, Cell & Environment 41, 10831097

Its not an overnight transformation, but a gradual shift back toward balance
