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In addition, WD6305, as a potent and selective proteolysis-targeting chimera (PROTAC) degrader of the METTL3-METTL14 complex, also offers a novel approach for the treatment of drug-resistant tumors [191]

All reagents and experiments conducted in this study are compliant with the institutional biological safety committee (SPROTO202200000081) of the University of Arkansas for Medical Sciences

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Adversely, iGluR antagonists CNQX, DNQX, and DL-2-amino-5-phosphonopentanoic acid (AP-5) show an inhibitory effect on Ca 2+ signaling and pollen tube growth (Michard et al., 2011)

Recent developments have also highlighted the potential of mRNA therapies, particularly cancer vaccines encoding tumour-specific antigens to elicit strong immune responses [222]