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Before recording the fluorescence intensity, we eliminated the background by adjusting the threshold based on autofluorescence from the negative control

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collapsin response-mediated protein-2, CRMP-2)] (124)

An elevated oxidative metabolism of astrocytes has been reported during the early stages of Alzheimer's disease (Duong et al

This work was supported by the Ministry of Research, Innovation and Digitization, within PNCDI-IV and core programs (PN), Romanian Ministry for EU Projects PNRR-III-C9-2022-I8 (contract no.760110), projects PN-IV-P2-2.1-TE-2023-1875, ELI-RO-39-2023, PN-IV-P1-PCE-2023-1836 of CNCS-UEFISCDI

Thus, similar possible relationship between high amount hot chili pepper consumption and several peripheral pain inductions should be investigated by future studies
