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For simplicity, we assume that the activations of GCL and GPX are equal, though that may not be the case

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Thymosin Beta-4 Modulates Cardiac Remodeling by Regulating ROCK1 Expression in Adult Mammals, Maar K, Thatcher JE, Karpov E, Rendeki S, Gallyas F Jr, Bock-Marquette I, International Journal of Molecular Sciences, International Journal of Molecular Sciences, 2025;26(9):4131

Red blood cell membrane essential fatty acid metabolism in early psychotic patients following antipsychotic drug treatment

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Once both substrates are bound at the enzyme's active site, the monomeric GST interacts with another substrate-bound GST monomer and catalyzes a disulphide bridge between the two glutathione molecules