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Pharmacological inhibition of the adenosine A2A receptor can also reverse myeloid-mediated immunosuppression and rescue CD8 T-cell function, sensitizing tumors to similar metastatic castration-resistant prostate cancer to atezolizumab and inducing a favorable ORR [182]
-Glucans, History, and the Present: Immunomodulatory Aspects and Mechanisms of Action
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However, reduction in intake of antioxidant substances may increase the chance of oxidative stress which may lead to cell damage [42]
Once more, the small sample size may have influenced the results [86]
