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A noteworthy question, however, is whether the sulfating activity of another SULT2B1 variant, SULT2B1a, can be influenced by nonsynonymous coding SNPs (cSNPs) in SULT2B1 , thus leading to distinct physiological and pathological effects related to steroid metabolism in different individuals
PMC 4962419

Francescone R, Barbosa Vendramini-Costa D, Franco-Barraza J, Wagner J, Muir A, Lau AN, et al

Antiepileptic Drug Discov
