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Furthermore, given the prevalent BBB dysfunction in AD, the efficiency of hepatokines across the BBB may be significantly altered, impacting the therapeutic potential of these molecules

Initially, it received FDA approval for treating type 2 diabetes

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A highly water-soluble disulfonated tetrazolium salt as a chromogenic indicator for NADH as well as cell viability

transporter-mediated GABA release has been implicated in this tonic inhibition 99,100,101,102 , although some studies suggest that such a mechanism may not be physiologically relevant 103,104

301 Cognitive load and attentional demands can influence motor performance by affecting these cortical areas, potentially leading to decreased movement accuracy and increased injury risk under conditions of mental fatigue or distraction