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A biodistribution study revealed that the accumulation of DOX in tumors was over twice as high in the DOX/LAAM GSH-CQD group compared to any other organs, whereas free DOX was mainly distributed in the liver, and the fluorescence intensity of the tumor was only half that of the liver at this time point (Fig

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The main aspect to consider is that within cells GSH is 300- to 800-fold higher than GSSG

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