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While oral supplements are available, B12 injections offer better absorption, especially for those with gastrointestinal issues or poor nutrient absorption
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Furthermore, IGFBPs other than IGFBP-3 may play a role in the access of IGF-I to various tissues (129)

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It works by inhibiting the NNMT enzyme, which is associated with fat storage, insulin resistance, and reduced cellular energy

Open-label trial of recombinant human insulin-like growth factor 1/recombinant human insulin-like growth factor binding protein 3 in myotonic dystrophy type 1
