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Description
Currently, eloralintide is undergoing clinical evaluation in Phase 1 and Phase 2 trials for the treatment of obesity and overweight conditions, aiming to assess its safety, tolerability, and efficacy, both as a monotherapy and in combination with other agents such as tirzepatide (Figure 2f)
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10.1038/s41419-018-1010-2 Cell Death Dis
c-Myc increases the levels of glycolytic and PPP enzymes, including LDHA, GLUT1, PKM2, and G6PD [63, 64], and enhances DNL and cholesterol synthesis by transcriptionally activating SREBP1/2 [134]
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