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ROS are mainly produced in mitochondria during aerobic respiration, especially at complexes I and III of the electron transport chain [162, 163]

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Procopiou PA, Anderson NA, Barrett J, Barrett TN, Crawford MHJ, Fallon BJ, et al

Although leptin has also a crucial role in rodent pregnancy, the main trigger for leptin induction in mice is unknown

Shawn, the Drosophila homolog of SLC25A39/40, is a mitochondrial carrier that promotes neuronal survival

Proteins required for cAMP signaling such as protein kinase A (PKA) and exchange protein directly activated by cAMP (EPAC-1) were found to be increased along with restored GLP-1/cAMP levels, indicating cardioprotection [22]