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ROS and oxidatively modified macromolecules function as damage-associated molecular patterns (DAMPs), engaging pattern recognition receptors (PRRs) on microglia, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), to initiate inflammatory cascades (Block et al., 2007)

In these mice, reduced expression of Sirt6 is accompanied by significant activation of Nrf2/HO-1 as downstream targets of Sirt6

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Due to the presence of numerous endogenous interfering substances in biological samples, efficient separation and enrichment of trace toxic components and their metabolites are essential

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Green synthesis of silver nanoparticles using Lysiloma acapulcensis exhibit high-antimicrobial activity