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5.3 Controlled drug release Controlled drug release can prevent premature drug degradation and systemic exposure, enabling precise drug delivery at the target site while maintaining stable local concentrations and minimizing resistance escape

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doi: 10.1002/hep.24485 132 Mestre-FarreraABruch-OmsMPeaRRodrguez-MoratJAlba-CastellnLComermaLet al

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10.1159/000026149 Neuroepidemiology 135 Okado-MatsumotoA.FridovichI