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The replacement of protons by deuterium nuclei at a specific position inside the molecule has two effects: (i) a signal decrease in the QELT spectra for the corresponding chemical group itself and (ii) a change in the structure of multiplets due to change in scalar coupling, which can potentially induce changes in signal intensity, phase, line width, and chemical shift of the spectral pattern of the different coupling partners

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CrossRef Association between alcohol consumption and risk of developing tuberculosis in patients with diabetes: a nationwide retrospective cohort study Chiwook Chung, Kyu Na Lee, Kyungdo Han, Junhee Park, Dong Wook Shin, Sei Won Lee Respiratory Research.2024;[Epub] CrossRef Validation of self-reported morbidities in the Korean Atomic Bomb Survivor Cohort Ansun Jeong, Somin Jeon, Seong-geun Moon, Mi Kyung Kim, Inah Kim, Yu-Mi Kim, Boyoung Park Epidemiology and Health.2024

H4K12la levels were shown to be significantly higher in TNBC by Kla proteomics analysis

4.6.2 Proteostasis Protein homeostasis, or proteostasis, is essential for normal cellular function and involves maintaining proteins in appropriate conformation, concentration, and location within the cell [211]