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GrarupNSulemPSandholtCHThorleifssonGAhluwaliaTSSteinthorsdottirVet al
In another set of experiments, cells were preincubated with 10 M LY294002 for 30 min at 37 C and then stimulated with bTNF- for 5 min
When IDO-1 is activated, it negatively impacts cellular energy metabolism by catalyzing the conversion of tryptophan into kynurenine, leading to tryptophan depletion
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