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Furthermore, antioxidant treatment reversed ER stress and normalized the expression of related pathway molecules, which manifested that redox imbalance promoted UPR activation (109)

rnNicotinamide adenine dinucleotide (NAD+) is a powerful coenzyme found in every cell of the body, playing a crucial role in energy production, DNA repair, and cellular function

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This is why it is often referred to as the master antioxidant

MyD88, Myeloid differentiation primary response protein 88