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Fan Y-Y, Davidson LA, Callaway ES et al (2015) A bioassay to measure energy metabolism in mouse colonic crypts, organoids, and sorted stem cells

BMJ Open 10 (11), e040527

The IGF-1 signaling pathway is frequently activated in cancer cells, and it shifts metabolic resources toward growth and proliferation

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Downstream signaling from RTK activation: Receptor binding triggers autophosphorylation recruiting adaptor proteins initiating multiple pathways

Trx efficiently reduced both LMW and protein persulfides, leading to H 2 S release