increased glutathione in acute myeloid leukemia APR-246 induces early cell death by ferroptosis Chemoresistance of TP53 mutant acute
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159(4):1480-1491.e2

Increased activation ability of monocytes from ALS patients

These mechanisms are part of why the peptides have attracted attention

[DOI] [PubMed] [Google Scholar] 83.Yarden Y

Usp9x contributes to the development of sepsis-induced acute kidney injury by promoting inflammation and apoptosis in renal tubular epithelial cells via activation of the TLR4/nf-b pathway

In the immune response, tumor cells exhibit high levels of CD47 expression, which impedes phagocytosis by macrophages through its binding to SIRP on the macrophage surface, thereby facilitating immune evasion
