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When the microneedling device is applied to the skin, it creates thousands of microscopic channels

So supplementing while on a diet may be beneficial, though you should run it by a doctor first

10.1038/s41467-017-00479-7 177

Chronic inflammation is sustained by elevated levels of cytokines (e.g., IL-1, IL-6, and TNF-), chemokines (CCL2, CCL5), and prostaglandins, with the activation of nuclear factor B (NF-B) and MAPK pathways, which further promote angiogenesis and cellular adhesion

9 Long-term side effects Regular use may eventually cause: rapid or irregular heartbeat, high blood pressure and potential inflammation of heart valves skin disorders, vitamin deficiency, flushed or pale skin stomach ulcers and malnutrition mental health and behavioural problems dizziness and difficulty breathing loss of coordination and physical collapse unusual tiredness or weakness repetitive physical actions convulsions, coma, and death

Yokogoshi and Terashima, 2000)