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they mediate visceral nociception, and are activated by mechanical and chemical irritants in the upper airways, transmitting to the brainstem nuclei and central nervous system (CNS) (Mazzone and Undem 2016)

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The tumor microenvironment is generally enriched in different lipid species [99,100]

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[DOI] [PMC free article] [PubMed] [Google Scholar] Riesenberg S, Groetchen A, Siddaway R, Bald T, Reinhardt J, Smorra D, Kohlmeyer J, Renn M, Phung B, Aymans P, et al

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[DOI] [PubMed] [Google Scholar] Solomon J

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Excessive copper levels in the liver have been demonstrated to result in a number of physiological consequences, including mitochondrial dysfunction, the downregulation of copper influx, the upregulation of metallothioneins (MTs), and ultimately, cell death

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