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Nat Rev Cancer (2016) 16(6):34558
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[DOI] [PubMed] [Google Scholar] 146.Huang S.C., Zhang L., Sung Y.S., Chen C.L., Kao Y.C., Agaram N.P., Singer S., Tap W.D., DAngelo S., Antonescu C.R

found that CBP (cAMP-responsive element-binding (CREB)-binding protein) and SIRT4 in PDAC cells bind the K44 site of BCAT2 to acetylate this site, which further promotes the degradation of BCAT2 through the ubiquitin-protein pathway, reduces the metabolic rate of BCAAs in PDAC, and, in turn, inhibits the growth of tumor cells

Oral D-4F reduces atherosclerosis in Apo E-deficient and LDLR-deficient mice, significantly increasing cholesterol emigration from mouse macrophages by mediating cellular signal transduction 146

Brain development in rodents and humans: identifying benchmarks of maturation and vulnerability to injury across species
