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Notably, SHLPs 2 and 3 significantly reduced staurosporine-dependent apoptosis and the generation of reactive oxygen species, while increasing mi-tochondrial respiration and ATP production in vitro [22]
10.1186/s12967-016-1109-0 16 CoricD.PettineK.SumichA.BoltesM

Medications : Prolonged use of certain drugs like metformin or proton pump inhibitors can interfere with B12 absorption

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ABCC1 may be relatively more important in terminal detoxification in nonpolarized cell types (Nies and Keppler, 2007)