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Both CB1 and CB2 skin receptors, which are present in epidermal keratinocytes, cutaneous nerve fibers, dermal cells, melanocytes, eccrine sweat glands, and hair follicles [96,97,98], can be modulated by endocannabinoids, with the most studied being N-arachidonoyl ethanolamide (AEA), 2-arachidonoyl glycerol (2-AG), N-palmitoyl ethanolamide (PEA), N-alpha-linolenoyl ethanolamide (ALEA), N-linoleoyl ethanolamide (LEA), N-oleoyl ethanolamide (OEA), N-stearoyl ethanolamide (SEA), N-eicosapentaenoyl ethanolamide (EPEA), and N-docosahexaenoyl ethanolamide (DHEA) [99,100,101,102,103]

Ambien and Suboxone are known to have a major interaction effect

Unmasking the Silent Threat: The Surprising Diseases Linked to Antioxidant Deficiency A deficiency of antioxidants can lead to oxidative stress and increased free radicals, which cause various diseases

Start here If you suspect an autoimmune condition or have a diagnosis and want an integrated functional medicine partner in Edmonton, we can help with testing selection, interpretation, and a realistic, evidence-based plan that complements your existing care
