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It is characterized by inflammation and tissue injury, the driving factors in stone re-formation [3, 4]

39 , e3671 (2023)

doi: 10.3390/JCM14134536

GT: Funding acquisition, Supervision, Writing review and editing, Methodology

Unlike nociceptive or neuropathic pain, pharmacotherapy often yields modest effects and significant adverse effects [46, 396, 397, 398], necessitating a primary focus on nonpharmacological, mechanismbased interventions that target central dysregulation, dysfunctional pain processing, and associated psychosocial comorbidities [46, 264, 398, 399]

Lower the temperature of your hot water heater to minimize the risk of scalding