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[DOI] [PubMed] [Google Scholar] 68.Wartenberg K.E., Mayer S.A

In normal smokers, there is an increase in AP sites in the lungs, signifying active DNA repair, but this is significantly reduced in COPD patients, showing defective DNA repair in COPD

Selivanov V

Too much water and you are injecting larger volumes for the same dose

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However, it must be emphasized that the hypoxic responses, metabolic reprogramming, and accumulation of mutations potentially induced by this network draw upon concepts from certain areas of cancer research