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These findings demonstrate that intestinal inflammation modulates metal transporter expression and Mn distribution, influencing both local and systemic homeostasis

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Duplex-PCR coamplifies the region of interest and a control fragment (e.g., from the actin gene), which are more or less equally amplified

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The reversibility of Sglutathionylation/Snitrosylation proceeding by electrophilic attack by ROS/RNS on nucleophilic Cys residues provides a redox switch that controls the activity of signaling proteins, as well as regulation of tumor cell proliferation and programmed death