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For example, one of the most notable trials on the subject is the ELAD trial, which stands for Evaluating Liraglutide in Alzheimer's Disease. This 12-month RCT reported that liraglutide improves cognitive function and MRI volume in the temporal lobe and whole cortex, suggesting a potential benefit in treating Alzheimer's [21]

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FDA regulatory status - compounded GLP-1s: FDA proposed April 30, 2026 to exclude semaglutide and tirzepatide from 503B Bulks List