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Description
score 3: more than 50% irregular vascularization: increased number of capillaries, groups of thick-walled blood vessels irregularly arranged in the hypercellular tendon, and a nodular proliferation of blood vessels that can also be vertically directed in relation to their counterpart fibers
First comes adenylyl cyclase activation

10.2106/00004623-200604002-00005 133 KawaguchiY.OsadaR.KanamoriM.IshiharaH.OhmoriK.MatsuiH.et al (1999)

Such side effects differ from mild discomfort to serious issues

& Roca-Cusachs, P
Covington and Duff, 2021)