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Description
TCDD induced hepatic inflammation by accelerating arachidonic acids metabolism to up-regulate cyclooxygenase and lipoxygenases activity to produce leukotrienes, leading to steatohepatitis (Doskey et al
For standard curve generation, serial tenfold dilutions of S
158 HeymanE.GamelinF
[DOI] [PubMed] [Google Scholar] 102.Koch-Weser J., Browne T.R
The substance directly impacts T cells, affecting their growth and operation, and indirectly alters the activity of other immune cells that interact with T cells
This indicates that etomoxir modulates the inflammatory profile in the CNS and periphery
