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140 The mechanism by which blood excess vitamin B 12 occurs in patients in the intensive care unit is not clear, but some factors that may partially explain it include: 1) the elevated plasma levels of the cobalamin-carrier proteins, the transcobalamins I and III

Insufficient levels can hinder methylation, a crucial biochemical process that regulates neurotransmitter synthesis

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doi: 10.1080/02770900701421880