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Neurotransmitters Regulation and Food Intake: The Role of Dietary Sources in Neurotransmission

Perturbed NAD + metabolism in response to infection Microbial infection, including viruses and bacteria, causes an imbalance in the cellular redox environment, thus inducing different responses, e.g., antioxidant defenses, cell signaling, immune response and other processes

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SatijaABhupathirajuSNRimmEBSpiegelmanDChiuveSEBorgiLet al

In the canonical Notch signaling, the Notch ligand binding to its receptor results in the removal of the extracellular fraction, and then two protein hydrolysis by A disintegrin and metalloprotease (ADAM10/17) and subsequently by a -secretase, respectively, 233 results in the generation of the Notch active form, NICD (Notch intracellular domain)

doi: 10.1038/nrendo.2010.215