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Superoxide dismutase (SOD) is a reaction enzyme that catalyzes the dismutation of superoxide into oxygen and hydrogen peroxide and maintains the body redox state in coordination with CAT (7)

All secondary antibodies were purchased from Cell Signaling Technology (4408, 4409, 4412, 4413, Carlsbad, USA)

In response to the gamma radiation, a substantial increase in the level of GSH and related enzymes, that is, GST, GR, and GPx, were observed, with respect to the sham control

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Although innovations such as vascularization, genome editing, omics-techniques, high-content imaging (HCI), machine-learning-based and automated systems are already a reality in organoids, protocols need to continue evolving to improve tissue communication, cell patterning signals, body axis simulation and spatial-temporal control of differentiation (Lokai et al., 2023)

Nonenzymatic antioxidants are categorized as hydrophilic (vitamin C, uric acid, bilirubin, albumin, and flavonoids) or lipophilic (alpha-tocopherol, ubiquinol, and carotenoids) [16, 17]