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BREAST CANCER / BASIC RESEARCH Evaluating the potential causal relationship between carnitine-related metabolites and breast cancer: a Mendelian randomization and transcriptomic analysis More details Hide details 1 Department of Radiation Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China 2 Department of Oncology, The Sixth Affiliated Hospital of Guangxi Medical University, The First Peoples Hospital of Yulin, Yulin, Guangxi, China These authors had equal contribution to this work Submission date: 2025-10-16 Final revision date: 2025-12-18 Acceptance date: 2025-12-29 Online publication date: 2026-04-03 Publication date: 2026-06-30 Corresponding author Rensheng Wang Department of Radiation Oncology The First Affiliated Hospital of Guangxi Medical University No

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In light of the decline of sirtuin activity, the loss of NAD + levels is the primary cause of sirtuin inactivity, senescence, and ageing-related diseases [18]