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129 However, it has also been reported that HMOX1 can induce cell death by promoting intracellular ferrous accumulation

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These transcription factors promote the expression of genes involved in ion transport, antioxidant defense, and metabolic adjustments

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The hypothesized increase in calcium ion concentration within the cells, along with the potential activation of PKC, might lead to the exocytosis of vesicles that contain growth hormones