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Dermatological Conditions: Inflammatory skin issues like acne, eczema, or psoriasis can damage melanocytes

Conditions like pernicious anaemia (an autoimmune condition affecting a protein called intrinsic factor vital for B12 absorption), stomach issues (such as from reduced stomach acid or certain medications like proton pump inhibitors), intestinal disorders (like Crohns disease or coeliac disease), or even surgical removal of parts of the small intestine (e.g., gastric bypass surgery) can prevent proper absorption

Peer-review started: January 29, 2021 First decision: March 16, 2021 Article in press: April 29, 2021 Specialty type: Endocrinology and metabolism Country/Territory of origin: Italy Peer-review reports scientific quality classification Grade A (Excellent): 0 Grade B (Very good): B, B Grade C (Good): C, C Grade D (Fair): 0 Grade E (Poor): 0 P-Reviewer: Wu WJ, Xu J S-Editor: Gao CC L-Editor: Filipodia P-Editor: Ma YJ Contributor Information Marco Infante, UniCamillus, Saint Camillus International University of Health Sciences, Rome 00131, Italy

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32 , 33 Given that vitamin B 12 is involved in various functions in the body and is influenced by several clinical conditions known to be at risk, depending on the outcomes of COVID-19, identifying vitamin B 12 status is necessary for patients with current COVID-19 infection and those who have had COVID-19