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In a number of disease states, diffuse fibrosis can be assessed by quantitative CMR relaxometry, incorporating T 1 mapping with high reproducibility, however it was not possible in the present study to include T 1 mapping sequences
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The treated group (n = 40) received two daily doses of 300 mg of ALA (600 mg/day) and the control group (n = 40) received two daily doses of placebo

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